Clinical trial details

A Phase 3 Randomized Clinical Study of MK-4280A (Coformulated Favezelimab [MK-4280] Plus Pembrolizumab [MK-3475]) Versus Physicians Choice Chemotherapy in PD-(L)1-refractory, Relapsed or Refractory Classical Hodgkin Lymphoma (KEYFORM-008)

Identifier

MK-4280A-008

Sponsor

MERCK SHARP & DOHME CORP

Principal Investigator

CECILIA CARMEN CARPIO SEGURA

Service

Hematology


Study details

Tumor type: HODGKIN LYMPHOMA (HL)
Stage: Relapsed/Refractory
Main Investigational Agent : Immunotherapy
Phase: III
Randomization: Randomized

Molecular details

Biomarker: Not applicable
Biomarker criteria: Not applicable
Prescreening: Not applicable
Additional study population requirements: Not applicable

Drug details

Arm A: Coformulated Favezelimab/Pembrolizumab
Arm B: Chemotherapy (Bendamustine or Gemcitabine)

Links

Clinical Trials GOV (NCT identifier): NCT05508867
EU Clinical Trials Register (eudraCT Identifier): 2022-000371-39