Clinical trial details

A Phase 1 Open-Label, Dose Escalation and Expansion Trial to Investigate the Safety, Pharmacokinetics and Pharmacodynamics of CB307, a Trispecific Humabody® T-cell Enhancer, in Patients with PSMA+ Advanced and/or Metastatic Solid Tumours.

Identifier

CBT307-1

Sponsor

CRESCENDO BIOLOGICS

Principal Investigator

JOAN CARLES GALCERAN

Service

Oncology


Study details

Tumor type: PROSTATE
Stage: Advanced
Main Investigational Agent : Biespecific antibodies
Phase: I
Randomization: Non-randomized

Molecular details

Biomarker: PSMA pos
Biomarker criteria: Mandatory
Prescreening: Central
Additional study population requirements: Not applicable

Drug details

Arm A: CB307

Links

Clinical Trials GOV (NCT identifier): NCT04839991
EU Clinical Trials Register (eudraCT Identifier): 2019-004584-46